G608-0072 Screening compound: 4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzoic acid

G608-0072 Screening compound: 4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzoic acid
G608-0072 Screening compound: 4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound G608-0072
4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G608-0072

Molecular Formula

C21H19N5O3 (C21 H19 N5 O3)

Compound Name

4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzoic acid

IUPAC name

4-methoxy-3-{[5-methyl-2-(4-methylphenyl)-[124]triazolo[15-a]pyrimidin-7-yl]amino}benzoic acid

SMILES

Cc(cc1)ccc1-c1nn2c(Nc(cc(cc3)C(O)=O)c3OC)cc(C)nc2n1

InChI

InChI=1S/C21H19N5O3/c1-12-4-6-14(7-5-12)19-24-21-22-13(2)10-18(26(21)25-19)23-16-11-15(20(27)28)8-9-17(16)29-3/h4-11,23H,1-3H3,(H,27,28)

InChI Key

KDXJYAGDBQHAPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15022554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.533

Distribution Coefficient, logD

2.111

Water Solubility, LogSw

-4.26

Polar Surface Area

75.181

Acid Dissociation Constant (pKa)

4.98

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

G608-0072 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G608-0072 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G608-0072?
Check Price and Availability of G608-0072, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G608-0072 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G608-0072
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G608-0072
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G608-0072 available by request