G622-0719 Screening compound: butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydro-1,8-naphthyridine-3-amido}benzoate

G622-0719 Screening compound: butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydro-1,8-naphthyridine-3-amido}benzoate
G622-0719 Screening compound: butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydro-1,8-naphthyridine-3-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G622-0719
butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydro-1,8-naphthyridine-3-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G622-0719

Molecular Formula

C27H24FN3O4 (C27 H24 FN3 O4)

Compound Name

butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydro-1,8-naphthyridine-3-amido}benzoate

IUPAC name

butyl 4-{1-[(4-fluorophenyl)methyl]-2-oxo-12-dihydro-18-naphthyridine-3-amido}benzoate

SMILES

CCCCOC(c(cc1)ccc1NC(C1=Cc2cccnc2N(Cc(cc2)ccc2F)C1=O)=O)=O

InChI

InChI=1S/C27H24FN3O4/c1-2-3-15-35-27(34)19-8-12-22(13-9-19)30-25(32)23-16-20-5-4-14-29-24(20)31(26(23)33)17-18-6-10-21(28)11-7-18/h4-14,16H,2-3,15,17H2,1H3,(H,30,32)

InChI Key

SAJXOLMYBLIRBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08539132

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.427

Distribution Coefficient, logD

5.417

Water Solubility, LogSw

-5.26

Polar Surface Area

69.811

Acid Dissociation Constant (pKa)

9.05

Base Dissociation Constant (pKb)

-1.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G622-0719 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G622-0719 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G622-0719?
Check Price and Availability of G622-0719, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G622-0719 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G622-0719
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G622-0719
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G622-0719 available by request