G637-1343 Screening compound: 1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine

G637-1343 Screening compound: 1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine
G637-1343 Screening compound: 1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G637-1343
1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G637-1343

Molecular Formula

C27H37N3O4S (C27 H37 N3 O4 S)

Compound Name

1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine

IUPAC name

1-({3-methyl-5-[(1E)-2-(246-trimethylphenyl)ethenyl]-12-oxazol-4-yl}sulfonyl)-4-(4-methylpiperidine-1-carbonyl)piperidine

SMILES

CC(CC1)CCN1C(C(CC1)CCN1S(c1c(/C=C/c2c(C)cc(C)cc2C)onc1C)(=O)=O)=O

InChI

InChI=1S/C27H37N3O4S/c1-18-8-12-29(13-9-18)27(31)23-10-14-30(15-11-23)35(32,33)26-22(5)28-34-25(26)7-6-24-20(3)16-19(2)17-21(24)4/h6-7,16-18,23H,8-15H2,1-5H3

InChI Key

LSEHJDFRIFXLQU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15024548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.67

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.719

Distribution Coefficient, logD

4.719

Water Solubility, LogSw

-4.45

Polar Surface Area

70.113

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

0.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

G637-1343 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G637-1343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G637-1343?
Check Price and Availability of G637-1343, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G637-1343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G637-1343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G637-1343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G637-1343 available by request