G639-2049 Screening compound: {4-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]piperidino}[5-(3-pyridyl)-1H-pyrazol-3-yl]methanone

G639-2049 Screening compound: {4-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]piperidino}[5-(3-pyridyl)-1H-pyrazol-3-yl]methanone
G639-2049 Screening compound: {4-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]piperidino}[5-(3-pyridyl)-1H-pyrazol-3-yl]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-2049
{4-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]piperidino}[5-(3-pyridyl)-1H-pyrazol-3-yl]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-2049

Molecular Formula

C24H25N5O2 (C24 H25 N5 O2)

Compound Name

{4-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]piperidino}[5-(3-pyridyl)-1H-pyrazol-3-yl]methanone

IUPAC name

n/a

SMILES

O=C(C(CC1)CCN1C(c1n[nH]c(-c2cnccc2)c1)=O)N(CC1)Cc2c1cccc2

InChI

InChI=1S/C24H25N5O2/c30-23(29-13-7-17-4-1-2-5-20(17)16-29)18-8-11-28(12-9-18)24(31)22-14-21(26-27-22)19-6-3-10-25-15-19/h1-6,10,14-15,18H,7-9,11-13,16H2,(H,26,27)

InChI Key

VAHNQAPSIZJIMQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147654

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.371

Distribution Coefficient, logD

2.371

Water Solubility, LogSw

-2.57

Polar Surface Area

65.205

Acid Dissociation Constant (pKa)

11.62

Base Dissociation Constant (pKb)

3.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G639-2049 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Immunological Library (6760 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Others

References: we are preparing a list of scientific research reports with G639-2049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-2049?
Check Price and Availability of G639-2049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-2049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-2049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-2049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-2049 available by request