G642-0458 Screening compound: N~1~-{3-[4-acetyl-5-(2-pyridyl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl}-4-methylbenzamide

G642-0458 Screening compound: N~1~-{3-[4-acetyl-5-(2-pyridyl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl}-4-methylbenzamide
G642-0458 Screening compound: N~1~-{3-[4-acetyl-5-(2-pyridyl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl}-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G642-0458
N~1~-{3-[4-acetyl-5-(2-pyridyl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl}-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G642-0458

Molecular Formula

C23H20N4O3 (C23 H20 N4 O3)

Compound Name

N~1~-{3-[4-acetyl-5-(2-pyridyl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]phenyl}-4-methylbenzamide

IUPAC name

n/a

SMILES

CC(N1N=C(c2cccc(NC(c3ccc(C)cc3)=O)c2)OC1c1ncccc1)=O

InChI

InChI=1S/C23H20N4O3/c1-15-9-11-17(12-10-15)21(29)25-19-7-5-6-18(14-19)22-26-27(16(2)28)23(30-22)20-8-3-4-13-24-20/h3-14,23H,1-2H3,(H,25,29)/t23-/m1/s1

InChI Key

GZTIVALBTUVKIG-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD15025130

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.557

Distribution Coefficient, logD

3.557

Water Solubility, LogSw

-3.67

Polar Surface Area

67.390

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

0.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

G642-0458 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with G642-0458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G642-0458?
Check Price and Availability of G642-0458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G642-0458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G642-0458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G642-0458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G642-0458 available by request