G642-6624 Screening compound: 4-[4-acetyl-5-(6-methylpyridin-3-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate

G642-6624 Screening compound: 4-[4-acetyl-5-(6-methylpyridin-3-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate
G642-6624 Screening compound: 4-[4-acetyl-5-(6-methylpyridin-3-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G642-6624
4-[4-acetyl-5-(6-methylpyridin-3-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G642-6624

Molecular Formula

C28H23N3O5 (C28 H23 N3 O5)

Compound Name

4-[4-acetyl-5-(6-methylpyridin-3-yl)-4,5-dihydro-1,3,4-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate

IUPAC name

4-[4-acetyl-5-(6-methylpyridin-3-yl)-45-dihydro-134-oxadiazol-2-yl]-2-methoxyphenyl naphthalene-1-carboxylate

SMILES

CC(N1N=C(c(cc2)cc(OC)c2OC(c2cccc3ccccc23)=O)OC1c1cnc(C)cc1)=O

InChI

InChI=1S/C28H23N3O5/c1-17-11-12-21(16-29-17)27-31(18(2)32)30-26(36-27)20-13-14-24(25(15-20)34-3)35-28(33)23-10-6-8-19-7-4-5-9-22(19)23/h4-16,27H,1-3H3/t27-/m1/s1

InChI Key

OAOODKSWABXLIK-HHHXNRCGSA-N

MDL Number (MFCD)

MFCD15025614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.796

Distribution Coefficient, logD

4.796

Water Solubility, LogSw

-5.29

Polar Surface Area

72.018

Acid Dissociation Constant (pKa)

20.98

Base Dissociation Constant (pKb)

2.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

14.30

G642-6624 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G642-6624 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G642-6624?
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What is the minimum amount of G642-6624 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G642-6624
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G642-6624
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G642-6624 available by request