G657-0397 Screening compound: 3-{[4-(4-acetylphenyl)piperazino]carbonyl}-4-ethyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

G657-0397 Screening compound: 3-{[4-(4-acetylphenyl)piperazino]carbonyl}-4-ethyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one
G657-0397 Screening compound: 3-{[4-(4-acetylphenyl)piperazino]carbonyl}-4-ethyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G657-0397
3-{[4-(4-acetylphenyl)piperazino]carbonyl}-4-ethyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G657-0397

Molecular Formula

C24H28N6O3 (C24 H28 N6 O3)

Compound Name

3-{[4-(4-acetylphenyl)piperazino]carbonyl}-4-ethyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

IUPAC name

4-[4-(4-acetylphenyl)piperazine-1-carbonyl]-2-ethyl-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-trien-8-one

SMILES

CCN(c(n1nc2)c2C(N(CC2)CCN2c(cc2)ccc2C(C)=O)=O)C(CCNC2)=C2C1=O

InChI

InChI=1S/C24H28N6O3/c1-3-29-21-8-9-25-14-19(21)24(33)30-22(29)20(15-26-30)23(32)28-12-10-27(11-13-28)18-6-4-17(5-7-18)16(2)31/h4-7,15,25H,3,8-14H2,1-2H3

InChI Key

AUTBKEUPNFELPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27150077

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.882

Distribution Coefficient, logD

0.540

Water Solubility, LogSw

-2.19

Polar Surface Area

74.296

Acid Dissociation Constant (pKa)

21.69

Base Dissociation Constant (pKb)

7.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G657-0397 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G657-0397 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G657-0397?
Check Price and Availability of G657-0397, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G657-0397 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G657-0397
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G657-0397
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G657-0397 available by request