G659-0549 Screening compound: 4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide

G659-0549 Screening compound: 4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide
G659-0549 Screening compound: 4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G659-0549
4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G659-0549

Molecular Formula

C28H29N5O2 (C28 H29 N5 O2)

Compound Name

4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide

IUPAC name

4-{5-methyl-4-[(4-phenylpiperazin-1-yl)methyl]-13-oxazol-2-yl}-N-[(pyridin-2-yl)methyl]benzamide

SMILES

Cc1c(CN(CC2)CCN2c2ccccc2)nc(-c(cc2)ccc2C(NCc2ncccc2)=O)o1

InChI

InChI=1S/C28H29N5O2/c1-21-26(20-32-15-17-33(18-16-32)25-8-3-2-4-9-25)31-28(35-21)23-12-10-22(11-13-23)27(34)30-19-24-7-5-6-14-29-24/h2-14H,15-20H2,1H3,(H,30,34)

InChI Key

OURDQEZIPQCTAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15026502

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.410

Distribution Coefficient, logD

3.407

Water Solubility, LogSw

-3.44

Polar Surface Area

59.310

Acid Dissociation Constant (pKa)

11.58

Base Dissociation Constant (pKb)

5.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G659-0549 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G659-0549 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G659-0549?
Check Price and Availability of G659-0549, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G659-0549 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G659-0549
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G659-0549
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G659-0549 available by request