G663-0820 Screening compound: 3-[(2-chloro-4-fluorophenyl)methyl]-3H,4H,6H,7H,8H,9H-pyrimido[4,5-b]quinolin-4-one

G663-0820 Screening compound: 3-[(2-chloro-4-fluorophenyl)methyl]-3H,4H,6H,7H,8H,9H-pyrimido[4,5-b]quinolin-4-one
G663-0820 Screening compound: 3-[(2-chloro-4-fluorophenyl)methyl]-3H,4H,6H,7H,8H,9H-pyrimido[4,5-b]quinolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G663-0820
3-[(2-chloro-4-fluorophenyl)methyl]-3H,4H,6H,7H,8H,9H-pyrimido[4,5-b]quinolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G663-0820

Molecular Formula

C18H15ClFN3O (C18 H15 ClFN3 O)

Compound Name

3-[(2-chloro-4-fluorophenyl)methyl]-3H,4H,6H,7H,8H,9H-pyrimido[4,5-b]quinolin-4-one

IUPAC name

3-[(2-chloro-4-fluorophenyl)methyl]-3H4H6H7H8H9H-pyrimido[45-b]quinolin-4-one

SMILES

O=C1N(Cc(ccc(F)c2)c2Cl)C=Nc2c1cc(CCCC1)c1n2

InChI

InChI=1S/C18H15ClFN3O/c19-15-8-13(20)6-5-12(15)9-23-10-21-17-14(18(23)24)7-11-3-1-2-4-16(11)22-17/h5-8,10H,1-4,9H2

InChI Key

ZIPVTTQQGXZYFV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15027080

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.79

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.179

Distribution Coefficient, logD

4.176

Water Solubility, LogSw

-4.50

Polar Surface Area

36.952

Acid Dissociation Constant (pKa)

22.79

Base Dissociation Constant (pKb)

5.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G663-0820 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G663-0820 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G663-0820?
Check Price and Availability of G663-0820, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G663-0820 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G663-0820
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G663-0820
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G663-0820 available by request