G675-0249 Screening compound: N2-(4-methoxyphenyl)-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

G675-0249 Screening compound: N2-(4-methoxyphenyl)-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide
G675-0249 Screening compound: N2-(4-methoxyphenyl)-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G675-0249
N2-(4-methoxyphenyl)-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G675-0249

Molecular Formula

C21H22N4O6S (C21 H22 N4 O6 S)

Compound Name

N2-(4-methoxyphenyl)-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

IUPAC name

N2-(4-methoxyphenyl)-N5-[(345-trimethoxyphenyl)methyl]-134-thiadiazole-25-dicarboxamide

SMILES

COc(cc1)ccc1NC(c1nnc(C(NCc(cc2OC)cc(OC)c2OC)=O)s1)=O

InChI

InChI=1S/C21H22N4O6S/c1-28-14-7-5-13(6-8-14)23-19(27)21-25-24-20(32-21)18(26)22-11-12-9-15(29-2)17(31-4)16(10-12)30-3/h5-10H,11H2,1-4H3,(H,22,26)(H,23,27)

InChI Key

XHSIAIFFGYEMLT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15028556

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.445

Distribution Coefficient, logD

2.444

Water Solubility, LogSw

-3.14

Polar Surface Area

101.769

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

-1.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G675-0249 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G675-0249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G675-0249?
Check Price and Availability of G675-0249, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G675-0249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G675-0249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G675-0249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G675-0249 available by request