G675-1813 Screening compound: N2-phenyl-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

G675-1813 Screening compound: N2-phenyl-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide
G675-1813 Screening compound: N2-phenyl-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G675-1813
N2-phenyl-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G675-1813

Molecular Formula

C20H20N4O5S (C20 H20 N4 O5 S)

Compound Name

N2-phenyl-N5-[(3,4,5-trimethoxyphenyl)methyl]-1,3,4-thiadiazole-2,5-dicarboxamide

IUPAC name

N2-phenyl-N5-[(345-trimethoxyphenyl)methyl]-134-thiadiazole-25-dicarboxamide

SMILES

COc1cc(CNC(c2nnc(C(Nc3ccccc3)=O)s2)=O)cc(OC)c1OC

InChI

InChI=1S/C20H20N4O5S/c1-27-14-9-12(10-15(28-2)16(14)29-3)11-21-17(25)19-23-24-20(30-19)18(26)22-13-7-5-4-6-8-13/h4-10H,11H2,1-3H3,(H,21,25)(H,22,26)

InChI Key

OGJKLDGOHVJWBN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15028861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.271

Distribution Coefficient, logD

2.271

Water Solubility, LogSw

-3.10

Polar Surface Area

94.225

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

-1.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G675-1813 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G675-1813 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G675-1813?
Check Price and Availability of G675-1813, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G675-1813 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G675-1813
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G675-1813
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G675-1813 available by request