G677-0029 Screening compound: ethyl 2-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-amido}benzoate

G677-0029 Screening compound: ethyl 2-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-amido}benzoate
G677-0029 Screening compound: ethyl 2-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G677-0029
ethyl 2-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G677-0029

Molecular Formula

C22H19N3O3S (C22 H19 N3 O3 S)

Compound Name

ethyl 2-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-amido}benzoate

IUPAC name

ethyl 2-{3-methyl-6-phenylimidazo[21-b][13]thiazole-2-amido}benzoate

SMILES

CCOC(c(cccc1)c1NC(c(s1)c(C)n2c1nc(-c1ccccc1)c2)=O)=O

InChI

InChI=1S/C22H19N3O3S/c1-3-28-21(27)16-11-7-8-12-17(16)23-20(26)19-14(2)25-13-18(24-22(25)29-19)15-9-5-4-6-10-15/h4-13H,3H2,1-2H3,(H,23,26)

InChI Key

CMMLRHJUPSOKGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08318726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.796

Distribution Coefficient, logD

4.653

Water Solubility, LogSw

-4.44

Polar Surface Area

52.589

Acid Dissociation Constant (pKa)

7.81

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G677-0029 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G677-0029 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G677-0029?
Check Price and Availability of G677-0029, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G677-0029 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G677-0029
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G677-0029
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G677-0029 available by request