G677-0068 Screening compound: 1-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

G677-0068 Screening compound: 1-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine
G677-0068 Screening compound: 1-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G677-0068
1-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G677-0068

Molecular Formula

C24H21F3N4OS (C24 H21 F3 N4 OS)

Compound Name

1-{3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

IUPAC name

1-{3-methyl-6-phenylimidazo[21-b][13]thiazole-2-carbonyl}-4-[3-(trifluoromethyl)phenyl]piperazine

SMILES

Cc1c(C(N(CC2)CCN2c2cc(C(F)(F)F)ccc2)=O)sc2nc(-c3ccccc3)cn12

InChI

InChI=1S/C24H21F3N4OS/c1-16-21(33-23-28-20(15-31(16)23)17-6-3-2-4-7-17)22(32)30-12-10-29(11-13-30)19-9-5-8-18(14-19)24(25,26)27/h2-9,14-15H,10-13H2,1H3

InChI Key

YWYLTXOWZJPLSL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08318749

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.52

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.149

Distribution Coefficient, logD

5.146

Water Solubility, LogSw

-5.02

Polar Surface Area

29.350

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

5.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G677-0068 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G677-0068 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G677-0068?
Check Price and Availability of G677-0068, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G677-0068 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G677-0068
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G677-0068
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G677-0068 available by request