G700-0464 Screening compound: 4-ethyl-N~3~-[2-(4-ethylpiperazino)ethyl]-7-(4-methoxybenzyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

G700-0464 Screening compound: 4-ethyl-N~3~-[2-(4-ethylpiperazino)ethyl]-7-(4-methoxybenzyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide
G700-0464 Screening compound: 4-ethyl-N~3~-[2-(4-ethylpiperazino)ethyl]-7-(4-methoxybenzyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G700-0464
4-ethyl-N~3~-[2-(4-ethylpiperazino)ethyl]-7-(4-methoxybenzyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G700-0464

Molecular Formula

C28H39N7O3 (C28 H39 N7 O3)

Compound Name

4-ethyl-N~3~-[2-(4-ethylpiperazino)ethyl]-7-(4-methoxybenzyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

IUPAC name

2-ethyl-N-[2-(4-ethylpiperazin-1-yl)ethyl]-11-[(4-methoxyphenyl)methyl]-8-oxo-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-triene-4-carboxamide

SMILES

CCN1CCN(CCNC(c(cnn23)c3N(CC)C(CCN(Cc(cc3)ccc3OC)C3)=C3C2=O)=O)CC1

InChI

InChI=1S/C28H39N7O3/c1-4-31-14-16-32(17-15-31)13-11-29-26(36)23-18-30-35-27(23)34(5-2)25-10-12-33(20-24(25)28(35)37)19-21-6-8-22(38-3)9-7-21/h6-9,18H,4-5,10-17,19-20H2,1-3H3,(H,29,36)

InChI Key

ZFGVZXBFVBYXJC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27151791

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

521.66

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.963

Distribution Coefficient, logD

1.171

Water Solubility, LogSw

-2.58

Polar Surface Area

71.460

Acid Dissociation Constant (pKa)

12.41

Base Dissociation Constant (pKb)

8.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.60

G700-0464 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with G700-0464 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G700-0464?
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What is the minimum amount of G700-0464 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G700-0464
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G700-0464
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G700-0464 available by request