G714-0023 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea

G714-0023 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea
G714-0023 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G714-0023
3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G714-0023

Molecular Formula

C18H17ClFN3O2 (C18 H17 ClFN3 O2)

Compound Name

3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea

IUPAC name

3-[(1-acetyl-23-dihydro-1H-indol-5-yl)methyl]-1-(3-chloro-4-fluorophenyl)urea

SMILES

CC(N(CC1)c2c1cc(CNC(Nc(cc1)cc(Cl)c1F)=O)cc2)=O

InChI

InChI=1S/C18H17ClFN3O2/c1-11(24)23-7-6-13-8-12(2-5-17(13)23)10-21-18(25)22-14-3-4-16(20)15(19)9-14/h2-5,8-9H,6-7,10H2,1H3,(H2,21,22,25)

InChI Key

QKPHZGOYAWNMEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27153243

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.8

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.079

Distribution Coefficient, logD

3.079

Water Solubility, LogSw

-3.55

Polar Surface Area

50.282

Acid Dissociation Constant (pKa)

10.38

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G714-0023 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
  • PPI modulators
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with G714-0023 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G714-0023?
Check Price and Availability of G714-0023, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G714-0023 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G714-0023
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G714-0023
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G714-0023 available by request