G747-0408 Screening compound: 3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-1,2-dihydropyridin-2-one

G747-0408 Screening compound: 3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-1,2-dihydropyridin-2-one
G747-0408 Screening compound: 3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G747-0408
3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G747-0408

Molecular Formula

C24H26FN3O2 (C24 H26 FN3 O2)

Compound Name

3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-1,2-dihydropyridin-2-one

IUPAC name

3-[(4-fluorophenyl)(piperidin-1-yl)methyl]-4-hydroxy-6-methyl-1-[(pyridin-2-yl)methyl]-12-dihydropyridin-2-one

SMILES

CC(N1Cc2ncccc2)=CC(O)=C(C(c(cc2)ccc2F)N2CCCCC2)C1=O

InChI

InChI=1S/C24H26FN3O2/c1-17-15-21(29)22(24(30)28(17)16-20-7-3-4-12-26-20)23(27-13-5-2-6-14-27)18-8-10-19(25)11-9-18/h3-4,7-12,15,23,29H,2,5-6,13-14,16H2,1H3/t23-/m0/s1

InChI Key

CKWIAMIFAODNAO-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD09540044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.219

Distribution Coefficient, logD

1.311

Water Solubility, LogSw

-3.12

Polar Surface Area

42.901

Acid Dissociation Constant (pKa)

5.50

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

G747-0408 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G747-0408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G747-0408?
Check Price and Availability of G747-0408, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G747-0408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G747-0408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G747-0408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G747-0408 available by request