G747-0521 Screening compound: 1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-1,2-dihydropyridin-2-one

G747-0521 Screening compound: 1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-1,2-dihydropyridin-2-one
G747-0521 Screening compound: 1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-1,2-dihydropyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G747-0521
1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-1,2-dihydropyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G747-0521

Molecular Formula

C23H27N3O3 (C23 H27 N3 O3)

Compound Name

1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-1,2-dihydropyridin-2-one

IUPAC name

1-[(furan-2-yl)methyl]-4-hydroxy-6-methyl-3-[(4-methylpiperazin-1-yl)(phenyl)methyl]-12-dihydropyridin-2-one

SMILES

CC(N1Cc2ccco2)=CC(O)=C(C(c2ccccc2)N2CCN(C)CC2)C1=O

InChI

InChI=1S/C23H27N3O3/c1-17-15-20(27)21(23(28)26(17)16-19-9-6-14-29-19)22(18-7-4-3-5-8-18)25-12-10-24(2)11-13-25/h3-9,14-15,22,27H,10-13,16H2,1-2H3/t22-/m0/s1

InChI Key

YKPLNZIYTOHJAZ-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD09237660

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.671

Distribution Coefficient, logD

2.671

Water Solubility, LogSw

-2.71

Polar Surface Area

44.583

Acid Dissociation Constant (pKa)

5.50

Base Dissociation Constant (pKb)

8.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

G747-0521 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

GPCR Targeted Library (31838 compounds)

Anti-HIV1 Library (19540 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G747-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G747-0521?
Check Price and Availability of G747-0521, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G747-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G747-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G747-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G747-0521 available by request