G765-0145 Screening compound: N-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide

G765-0145 Screening compound: N-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide
G765-0145 Screening compound: N-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G765-0145
N-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G765-0145

Molecular Formula

C20H22FN3O2 (C20 H22 FN3 O2)

Compound Name

N-(3,4-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide

IUPAC name

N-(34-dihydro-2H-1-benzopyran-3-yl)-4-(4-fluorophenyl)piperazine-1-carboxamide

SMILES

O=C(NC(C1)COc2c1cccc2)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C20H22FN3O2/c21-16-5-7-18(8-6-16)23-9-11-24(12-10-23)20(25)22-17-13-15-3-1-2-4-19(15)26-14-17/h1-8,17H,9-14H2,(H,22,25)/t17-/m0/s1

InChI Key

HMPKHNXKDSCFPR-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD15034270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.779

Distribution Coefficient, logD

3.778

Water Solubility, LogSw

-4.05

Polar Surface Area

38.193

Acid Dissociation Constant (pKa)

15.97

Base Dissociation Constant (pKb)

7.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

G765-0145 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G765-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G765-0145?
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What is the minimum amount of G765-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G765-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G765-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G765-0145 available by request