G775-0667 Screening compound: N~1~-(4-chloro-2-methoxy-5-methylphenyl)-2-[6-(2,5-dimethylbenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]acetamide

G775-0667 Screening compound: N~1~-(4-chloro-2-methoxy-5-methylphenyl)-2-[6-(2,5-dimethylbenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]acetamide
G775-0667 Screening compound: N~1~-(4-chloro-2-methoxy-5-methylphenyl)-2-[6-(2,5-dimethylbenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G775-0667
N~1~-(4-chloro-2-methoxy-5-methylphenyl)-2-[6-(2,5-dimethylbenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G775-0667

Molecular Formula

C22H28ClN3O4S (C22 H28 ClN3 O4 S)

Compound Name

N~1~-(4-chloro-2-methoxy-5-methylphenyl)-2-[6-(2,5-dimethylbenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]acetamide

IUPAC name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-{6-[(25-dimethylphenyl)methyl]-11-dioxo-1lambda626-thiadiazinan-2-yl}acetamide

SMILES

Cc1cc(CN(CCCN2CC(Nc(c(OC)c3)cc(C)c3Cl)=O)S2(=O)=O)c(C)cc1

InChI

InChI=1S/C22H28ClN3O4S/c1-15-6-7-16(2)18(10-15)13-25-8-5-9-26(31(25,28)29)14-22(27)24-20-11-17(3)19(23)12-21(20)30-4/h6-7,10-12H,5,8-9,13-14H2,1-4H3,(H,24,27)

InChI Key

ANARJCQZKGLNMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27157681

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.568

Distribution Coefficient, logD

4.565

Water Solubility, LogSw

-4.61

Polar Surface Area

66.461

Acid Dissociation Constant (pKa)

9.71

Base Dissociation Constant (pKb)

0.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

G775-0667 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G775-0667 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G775-0667?
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What is the minimum amount of G775-0667 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G775-0667
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G775-0667
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G775-0667 available by request