G783-0318 Screening compound: 1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine

G783-0318 Screening compound: 1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine
G783-0318 Screening compound: 1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G783-0318
1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G783-0318

Molecular Formula

C17H19ClN4O3 (C17 H19 ClN4 O3)

Compound Name

1-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine

IUPAC name

1-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]-4-(oxolane-2-carbonyl)piperazine

SMILES

O=C(C1OCCC1)N(CC1)CCN1c1nc(-c(cc2)ccc2Cl)no1

InChI

InChI=1S/C17H19ClN4O3/c18-13-5-3-12(4-6-13)15-19-17(25-20-15)22-9-7-21(8-10-22)16(23)14-2-1-11-24-14/h3-6,14H,1-2,7-11H2/t14-/m0/s1

InChI Key

QVZHETSPJHJWRA-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15035798

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.82

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.640

Distribution Coefficient, logD

2.640

Water Solubility, LogSw

-3.42

Polar Surface Area

60.308

Acid Dissociation Constant (pKa)

20.94

Base Dissociation Constant (pKb)

0.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.10

G783-0318 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G783-0318 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G783-0318?
Check Price and Availability of G783-0318, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G783-0318 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G783-0318
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G783-0318
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G783-0318 available by request