G786-0551 Screening compound: 2,5-difluoro-N~1~-[4-(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-1-benzenesulfonamide

G786-0551 Screening compound: 2,5-difluoro-N~1~-[4-(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-1-benzenesulfonamide
G786-0551 Screening compound: 2,5-difluoro-N~1~-[4-(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-0551
2,5-difluoro-N~1~-[4-(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-0551

Molecular Formula

C18H13F2N3O2S2 (C18 H13 F2 N3 O2 S2)

Compound Name

2,5-difluoro-N~1~-[4-(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-1-benzenesulfonamide

IUPAC name

n/a

SMILES

Cc1csc2nc(-c(cc3)ccc3NS(c(cc(cc3)F)c3F)(=O)=O)cn12

InChI

InChI=1S/C18H13F2N3O2S2/c1-11-10-26-18-21-16(9-23(11)18)12-2-5-14(6-3-12)22-27(24,25)17-8-13(19)4-7-15(17)20/h2-10,22H,1H3

InChI Key

AQJWVZJHEPKQHD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06703108

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.122

Distribution Coefficient, logD

4.111

Water Solubility, LogSw

-4.10

Polar Surface Area

50.316

Acid Dissociation Constant (pKa)

9.09

Base Dissociation Constant (pKb)

5.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

G786-0551 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Glucocorticoid receptors Library (4806 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G786-0551 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-0551?
Check Price and Availability of G786-0551, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-0551 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-0551
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-0551
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-0551 available by request