G786-1091 Screening compound: (2E)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide

G786-1091 Screening compound: (2E)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide
G786-1091 Screening compound: (2E)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1091
(2E)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1091

Molecular Formula

C15H11N3OS2 (C15 H11 N3 OS2)

Compound Name

(2E)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide

IUPAC name

(2E)-N-[4-(pyridin-2-yl)-13-thiazol-2-yl]-3-(thiophen-2-yl)prop-2-enamide

SMILES

O=C(/C=C/c1cccs1)Nc1nc(-c2ncccc2)cs1

InChI

InChI=1S/C15H11N3OS2/c19-14(7-6-11-4-3-9-20-11)18-15-17-13(10-21-15)12-5-1-2-8-16-12/h1-10H,(H,17,18,19)

InChI Key

ZIUQIINODRFTPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04409114

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

313.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.550

Distribution Coefficient, logD

3.549

Water Solubility, LogSw

-3.67

Polar Surface Area

42.957

Acid Dissociation Constant (pKa)

11.02

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

G786-1091 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Receptors Annotated Library (5376 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with G786-1091 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1091?
Check Price and Availability of G786-1091, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-1091 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1091
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1091
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1091 available by request