G786-1427 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)acetamide

G786-1427 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)acetamide
G786-1427 Screening compound: N-(4-methyl-1,3-thiazol-2-yl)-2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-1427
N-(4-methyl-1,3-thiazol-2-yl)-2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-1427

Molecular Formula

C18H15N5OS2 (C18 H15 N5 OS2)

Compound Name

N-(4-methyl-1,3-thiazol-2-yl)-2-({2-phenylimidazo[1,2-b]pyridazin-6-yl}sulfanyl)acetamide

IUPAC name

N-(4-methyl-13-thiazol-2-yl)-2-({2-phenylimidazo[12-b]pyridazin-6-yl}sulfanyl)acetamide

SMILES

Cc1csc(NC(CSc(cc2)nn3c2nc(-c2ccccc2)c3)=O)n1

InChI

InChI=1S/C18H15N5OS2/c1-12-10-26-18(19-12)21-16(24)11-25-17-8-7-15-20-14(9-23(15)22-17)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,19,21,24)

InChI Key

XMISJJUMUNXBKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06733453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.771

Distribution Coefficient, logD

3.763

Water Solubility, LogSw

-3.75

Polar Surface Area

51.754

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

G786-1427 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G786-1427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-1427?
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What is the minimum amount of G786-1427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-1427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-1427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-1427 available by request