G786-2063 Screening compound: 8-(3,4-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

G786-2063 Screening compound: 8-(3,4-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane
G786-2063 Screening compound: 8-(3,4-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2063
8-(3,4-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2063

Molecular Formula

C21H22F2N2O5S (C21 H22 F2 N2 O5 S)

Compound Name

8-(3,4-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-4,8-diazaspiro[4.5]decane

IUPAC name

8-(34-difluorobenzoyl)-4-(4-methoxybenzenesulfonyl)-1-oxa-48-diazaspiro[4.5]decane

SMILES

COc(cc1)ccc1S(N1C(CC2)(CCN2C(c(cc2)cc(F)c2F)=O)OCC1)(=O)=O

InChI

InChI=1S/C21H22F2N2O5S/c1-29-16-3-5-17(6-4-16)31(27,28)25-12-13-30-21(25)8-10-24(11-9-21)20(26)15-2-7-18(22)19(23)14-15/h2-7,14H,8-13H2,1H3

InChI Key

INQCUGUEJURBRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07649068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.358

Distribution Coefficient, logD

2.358

Water Solubility, LogSw

-2.82

Polar Surface Area

63.119

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

-3.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G786-2063 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G786-2063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2063?
Check Price and Availability of G786-2063, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2063 available by request