G786-2340 Screening compound: (2Z)-N-[3-(1,3-benzothiazol-2-yl)-6-ethyl-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-phenylprop-2-enamide

G786-2340 Screening compound: (2Z)-N-[3-(1,3-benzothiazol-2-yl)-6-ethyl-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-phenylprop-2-enamide
G786-2340 Screening compound: (2Z)-N-[3-(1,3-benzothiazol-2-yl)-6-ethyl-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G786-2340
(2Z)-N-[3-(1,3-benzothiazol-2-yl)-6-ethyl-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G786-2340

Molecular Formula

C25H23N3OS2 (C25 H23 N3 OS2)

Compound Name

(2Z)-N-[3-(1,3-benzothiazol-2-yl)-6-ethyl-4H,5H,6H,7H-thieno[2,3-c]pyridin-2-yl]-3-phenylprop-2-enamide

IUPAC name

(2Z)-N-[3-(13-benzothiazol-2-yl)-6-ethyl-4H5H6H7H-thieno[23-c]pyridin-2-yl]-3-phenylprop-2-enamide

SMILES

CCN(CC1)Cc2c1c(-c1nc(cccc3)c3s1)c(NC(/C=C\c1ccccc1)=O)s2

InChI

InChI=1S/C25H23N3OS2/c1-2-28-15-14-18-21(16-28)31-25(27-22(29)13-12-17-8-4-3-5-9-17)23(18)24-26-19-10-6-7-11-20(19)30-24/h3-13H,2,14-16H2,1H3,(H,27,29)

InChI Key

MQWDGLHECQAMSF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11984359

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.61

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.019

Distribution Coefficient, logD

5.792

Water Solubility, LogSw

-5.58

Polar Surface Area

35.750

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

7.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G786-2340 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

MCL1 Targeted Library (12200 compounds)

Protein-Protein Interaction Library (218420 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with G786-2340 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G786-2340?
Check Price and Availability of G786-2340, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G786-2340 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G786-2340
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G786-2340
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G786-2340 available by request