G808-0086 Screening compound: N-[5-chloro-2-({5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide

G808-0086 Screening compound: N-[5-chloro-2-({5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide
G808-0086 Screening compound: N-[5-chloro-2-({5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G808-0086
N-[5-chloro-2-({5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G808-0086

Molecular Formula

C24H24ClN3O3S (C24 H24 ClN3 O3 S)

Compound Name

N-[5-chloro-2-({5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide

IUPAC name

(3R5S7s)-N-[5-chloro-2-({5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methoxy)phenyl]adamantane-1-carboxamide

SMILES

O=C(C1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)Nc(cc(cc1)Cl)c1OCC(N=C1SC=CN11)=CC1=O

InChI

InChI=1S/C24H24ClN3O3S/c25-17-1-2-20(31-13-18-9-21(29)28-3-4-32-23(28)26-18)19(8-17)27-22(30)24-10-14-5-15(11-24)7-16(6-14)12-24/h1-4,8-9,14-16H,5-7,10-13H2,(H,27,30)

InChI Key

IZRMROMRRQITDS-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.99

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.743

Distribution Coefficient, logD

4.691

Water Solubility, LogSw

-5.05

Polar Surface Area

55.935

Acid Dissociation Constant (pKa)

8.29

Base Dissociation Constant (pKb)

-2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

G808-0086 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G808-0086 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G808-0086?
Check Price and Availability of G808-0086, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G808-0086 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G808-0086
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G808-0086
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G808-0086 available by request