G808-0491 Screening compound: N-[5-chloro-2-({2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide

G808-0491 Screening compound: N-[5-chloro-2-({2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide
G808-0491 Screening compound: N-[5-chloro-2-({2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G808-0491
N-[5-chloro-2-({2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G808-0491

Molecular Formula

C22H18ClN3O4S (C22 H18 ClN3 O4 S)

Compound Name

N-[5-chloro-2-({2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide

IUPAC name

N-[5-chloro-2-({2-methyl-5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methoxy)phenyl]-3-methoxybenzamide

SMILES

CC(SC1=NC(COc(ccc(Cl)c2)c2NC(c2cc(OC)ccc2)=O)=C2)=CN1C2=O

InChI

InChI=1S/C22H18ClN3O4S/c1-13-11-26-20(27)10-16(24-22(26)31-13)12-30-19-7-6-15(23)9-18(19)25-21(28)14-4-3-5-17(8-14)29-2/h3-11H,12H2,1-2H3,(H,25,28)

InChI Key

WUAVQTZIVFKONN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27162341

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.669

Distribution Coefficient, logD

3.635

Water Solubility, LogSw

-4.32

Polar Surface Area

63.964

Acid Dissociation Constant (pKa)

8.48

Base Dissociation Constant (pKb)

1.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G808-0491 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G808-0491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G808-0491?
Check Price and Availability of G808-0491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G808-0491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G808-0491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G808-0491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G808-0491 available by request