G812-0363 Screening compound: 4-[3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one

G812-0363 Screening compound: 4-[3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one
G812-0363 Screening compound: 4-[3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G812-0363
4-[3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G812-0363

Molecular Formula

C21H27N7O2 (C21 H27 N7 O2)

Compound Name

4-[3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one

IUPAC name

4-[3-(2-methoxyethyl)-3H-imidazo[45-b]pyridin-2-yl]-1-[4-(pyrimidin-2-yl)piperazin-1-yl]butan-1-one

SMILES

COCCn1c(nccc2)c2nc1CCCC(N(CC1)CCN1c1ncccn1)=O

InChI

InChI=1S/C21H27N7O2/c1-30-16-15-28-18(25-17-5-3-8-22-20(17)28)6-2-7-19(29)26-11-13-27(14-12-26)21-23-9-4-10-24-21/h3-5,8-10H,2,6-7,11-16H2,1H3

InChI Key

CNYOBDIMELUZEV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038416

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.404

Distribution Coefficient, logD

1.404

Water Solubility, LogSw

-1.55

Polar Surface Area

67.386

Acid Dissociation Constant (pKa)

20.72

Base Dissociation Constant (pKb)

3.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

G812-0363 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G812-0363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G812-0363?
Check Price and Availability of G812-0363, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G812-0363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G812-0363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G812-0363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G812-0363 available by request