G812-2241 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide

G812-2241 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide
G812-2241 Screening compound: 4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G812-2241
4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G812-2241

Molecular Formula

C24H31FN6O (C24 H31 FN6 O)

Compound Name

4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide

IUPAC name

4-{3-[(4-fluorophenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}-N-[2-(4-methylpiperazin-1-yl)ethyl]butanamide

SMILES

CN1CCN(CCNC(CCCc2nc3cccnc3n2Cc(cc2)ccc2F)=O)CC1

InChI

InChI=1S/C24H31FN6O/c1-29-14-16-30(17-15-29)13-12-26-23(32)6-2-5-22-28-21-4-3-11-27-24(21)31(22)18-19-7-9-20(25)10-8-19/h3-4,7-11H,2,5-6,12-18H2,1H3,(H,26,32)

InChI Key

TUIWJFFGVCCNCZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038637

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.345

Distribution Coefficient, logD

0.677

Water Solubility, LogSw

-2.04

Polar Surface Area

52.550

Acid Dissociation Constant (pKa)

13.80

Base Dissociation Constant (pKb)

7.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

G812-2241 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

MCL1 Targeted Library (12200 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G812-2241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G812-2241?
Check Price and Availability of G812-2241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G812-2241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G812-2241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G812-2241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G812-2241 available by request