G817-0556 Screening compound: 1-(piperidin-1-yl)-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)isoquinoline

G817-0556 Screening compound: 1-(piperidin-1-yl)-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)isoquinoline
G817-0556 Screening compound: 1-(piperidin-1-yl)-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)isoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G817-0556
1-(piperidin-1-yl)-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)isoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G817-0556

Molecular Formula

C24H25N3O (C24 H25 N3 O)

Compound Name

1-(piperidin-1-yl)-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)isoquinoline

IUPAC name

1-(piperidin-1-yl)-4-(1234-tetrahydroquinoline-1-carbonyl)isoquinoline

SMILES

O=C(c(c1ccccc11)cnc1N1CCCCC1)N(CCC1)c2c1cccc2

InChI

InChI=1S/C24H25N3O/c28-24(27-16-8-10-18-9-2-5-13-22(18)27)21-17-25-23(26-14-6-1-7-15-26)20-12-4-3-11-19(20)21/h2-5,9,11-13,17H,1,6-8,10,14-16H2

InChI Key

HJWDLBWRIMZYBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038814

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.405

Distribution Coefficient, logD

5.403

Water Solubility, LogSw

-5.75

Polar Surface Area

27.803

Acid Dissociation Constant (pKa)

23.47

Base Dissociation Constant (pKb)

5.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G817-0556 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G817-0556 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G817-0556?
Check Price and Availability of G817-0556, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G817-0556 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G817-0556
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G817-0556
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G817-0556 available by request