G824-0073 Screening compound: 5-chloro-3-[2-(3,4-dimethylphenyl)-2-oxoethyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

G824-0073 Screening compound: 5-chloro-3-[2-(3,4-dimethylphenyl)-2-oxoethyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one
G824-0073 Screening compound: 5-chloro-3-[2-(3,4-dimethylphenyl)-2-oxoethyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G824-0073
5-chloro-3-[2-(3,4-dimethylphenyl)-2-oxoethyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G824-0073

Molecular Formula

C18H16ClNO3 (C18 H16 ClNO3)

Compound Name

5-chloro-3-[2-(3,4-dimethylphenyl)-2-oxoethyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

IUPAC name

5-chloro-3-[2-(34-dimethylphenyl)-2-oxoethyl]-3-hydroxy-23-dihydro-1H-indol-2-one

SMILES

Cc(cc1)c(C)cc1C(CC(c(cc(cc1)Cl)c1N1)(C1=O)O)=O

InChI

InChI=1S/C18H16ClNO3/c1-10-3-4-12(7-11(10)2)16(21)9-18(23)14-8-13(19)5-6-15(14)20-17(18)22/h3-8,23H,9H2,1-2H3,(H,20,22)/t18-/m0/s1

InChI Key

JNPARLGJTDGTBI-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15039204

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.78

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.671

Distribution Coefficient, logD

3.669

Water Solubility, LogSw

-4.01

Polar Surface Area

53.818

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

-2.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

G824-0073 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Cardiovascular Library (22201 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G824-0073 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G824-0073?
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What is the minimum amount of G824-0073 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G824-0073
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G824-0073
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G824-0073 available by request