G851-1194 Screening compound: 5-({4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indole

G851-1194 Screening compound: 5-({4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indole
G851-1194 Screening compound: 5-({4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-1194
5-({4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-1194

Molecular Formula

C20H23N3O4S (C20 H23 N3 O4 S)

Compound Name

5-({4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indole

IUPAC name

5-({4-[(2H-13-benzodioxol-5-yl)methyl]piperazin-1-yl}sulfonyl)-23-dihydro-1H-indole

SMILES

O=S(c(cc1)cc2c1NCC2)(N1CCN(Cc(cc2)cc3c2OCO3)CC1)=O

InChI

InChI=1S/C20H23N3O4S/c24-28(25,17-2-3-18-16(12-17)5-6-21-18)23-9-7-22(8-10-23)13-15-1-4-19-20(11-15)27-14-26-19/h1-4,11-12,21H,5-10,13-14H2

InChI Key

VGWYEKJEGORJLK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040682

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

401.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.483

Distribution Coefficient, logD

2.388

Water Solubility, LogSw

-2.87

Polar Surface Area

64.450

Acid Dissociation Constant (pKa)

18.67

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

G851-1194 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G851-1194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-1194?
Check Price and Availability of G851-1194, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-1194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-1194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-1194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-1194 available by request