G852-0165 Screening compound: 6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-1,2-dihydroquinolin-2-one

G852-0165 Screening compound: 6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-1,2-dihydroquinolin-2-one
G852-0165 Screening compound: 6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G852-0165
6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G852-0165

Molecular Formula

C18H17N3O5S (C18 H17 N3 O5 S)

Compound Name

6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-1,2-dihydroquinolin-2-one

IUPAC name

6-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-12-dihydroquinolin-2-one

SMILES

O=C(c1ccco1)N(CC1)CCN1S(c(cc1)cc(C=C2)c1NC2=O)(=O)=O

InChI

InChI=1S/C18H17N3O5S/c22-17-6-3-13-12-14(4-5-15(13)19-17)27(24,25)21-9-7-20(8-10-21)18(23)16-2-1-11-26-16/h1-6,11-12H,7-10H2,(H,19,22)

InChI Key

ZDPSZHAZSVRFGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.306

Distribution Coefficient, logD

1.300

Water Solubility, LogSw

-2.47

Polar Surface Area

81.805

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

-3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G852-0165 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bromodomain Modulators Library (5801 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G852-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G852-0165?
Check Price and Availability of G852-0165, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G852-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G852-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G852-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G852-0165 available by request