G856-0392 Screening compound: 3-(2-CHLOROPHENYL)-N-(5-{IMIDAZO[1,2-A]PYRIMIDIN-2-YL}-2-METHOXYPHENYL)-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

G856-0392 Screening compound: 3-(2-CHLOROPHENYL)-N-(5-{IMIDAZO[1,2-A]PYRIMIDIN-2-YL}-2-METHOXYPHENYL)-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE
G856-0392 Screening compound: 3-(2-CHLOROPHENYL)-N-(5-{IMIDAZO[1,2-A]PYRIMIDIN-2-YL}-2-METHOXYPHENYL)-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G856-0392
3-(2-CHLOROPHENYL)-N-(5-{IMIDAZO[1,2-A]PYRIMIDIN-2-YL}-2-METHOXYPHENYL)-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G856-0392

Molecular Formula

C24H18ClN5O3 (C24 H18 ClN5 O3)

Compound Name

3-(2-CHLOROPHENYL)-N-(5-{IMIDAZO[1,2-A]PYRIMIDIN-2-YL}-2-METHOXYPHENYL)-5-METHYL-1,2-OXAZOLE-4-CARBOXAMIDE

IUPAC name

3-(2-chlorophenyl)-N-(5-{imidazo[12-a]pyrimidin-2-yl}-2-methoxyphenyl)-5-methyl-12-oxazole-4-carboxamide

SMILES

Cc1c(C(Nc(cc(cc2)-c3cn(cccn4)c4n3)c2OC)=O)c(-c(cccc2)c2Cl)no1

InChI

InChI=1S/C24H18ClN5O3/c1-14-21(22(29-33-14)16-6-3-4-7-17(16)25)23(31)27-18-12-15(8-9-20(18)32-2)19-13-30-11-5-10-26-24(30)28-19/h3-13H,1-2H3,(H,27,31)

InChI Key

WGQGTUWSIITYMY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05897840

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.89

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.681

Distribution Coefficient, logD

3.680

Water Solubility, LogSw

-4.39

Polar Surface Area

72.094

Acid Dissociation Constant (pKa)

10.27

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

G856-0392 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G856-0392 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G856-0392?
Check Price and Availability of G856-0392, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G856-0392 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G856-0392
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G856-0392
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G856-0392 available by request