G856-4448 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,4,5-trimethoxybenzamide

G856-4448 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,4,5-trimethoxybenzamide
G856-4448 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,4,5-trimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G856-4448
N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,4,5-trimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G856-4448

Molecular Formula

C22H22FNO6S2 (C22 H22 FNO6 S2)

Compound Name

N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-3,4,5-trimethoxybenzamide

IUPAC name

N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-345-trimethoxybenzamide

SMILES

COc1cc(C(NCC(c2cccs2)S(c(cc2)ccc2F)(=O)=O)=O)cc(OC)c1OC

InChI

InChI=1S/C22H22FNO6S2/c1-28-17-11-14(12-18(29-2)21(17)30-3)22(25)24-13-20(19-5-4-10-31-19)32(26,27)16-8-6-15(23)7-9-16/h4-12,20H,13H2,1-3H3,(H,24,25)/t20-/m0/s1

InChI Key

YFMQBIFEUBWWKD-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD06748605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.114

Distribution Coefficient, logD

3.114

Water Solubility, LogSw

-3.54

Polar Surface Area

78.149

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

-5.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

G856-4448 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G856-4448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G856-4448?
Check Price and Availability of G856-4448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G856-4448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G856-4448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G856-4448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G856-4448 available by request