G856-8300 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}prop-2-enamide

G856-8300 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}prop-2-enamide
G856-8300 Screening compound: (2E)-3-(3,4-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G856-8300
(2E)-3-(3,4-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G856-8300

Molecular Formula

C25H26N4O4S (C25 H26 N4 O4 S)

Compound Name

(2E)-3-(3,4-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}prop-2-enamide

IUPAC name

(2E)-3-(34-dimethoxyphenyl)-N-{2-[2-(4-methoxyphenyl)-6-methyl-[124]triazolo[32-b][13]thiazol-5-yl]ethyl}prop-2-enamide

SMILES

Cc1c(CCNC(/C=C/c(cc2)cc(OC)c2OC)=O)sc2nc(-c(cc3)ccc3OC)nn12

InChI

InChI=1S/C25H26N4O4S/c1-16-22(34-25-27-24(28-29(16)25)18-7-9-19(31-2)10-8-18)13-14-26-23(30)12-6-17-5-11-20(32-3)21(15-17)33-4/h5-12,15H,13-14H2,1-4H3,(H,26,30)

InChI Key

WNMBSUBPCSEBPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06749987

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.421

Distribution Coefficient, logD

4.421

Water Solubility, LogSw

-4.39

Polar Surface Area

68.555

Acid Dissociation Constant (pKa)

14.87

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G856-8300 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with G856-8300 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G856-8300?
Check Price and Availability of G856-8300, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G856-8300 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G856-8300
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G856-8300
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G856-8300 available by request