G856-8908 Screening compound: 4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one

G856-8908 Screening compound: 4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one
G856-8908 Screening compound: 4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G856-8908
4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G856-8908

Molecular Formula

C22H29N5O (C22 H29 N5 O)

Compound Name

4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one

IUPAC name

4-phenyl-1-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]piperazin-1-yl}butan-1-one

SMILES

O=C(CCCc1ccccc1)N(CC1)CCN1c(cc1)nnc1N1CCCC1

InChI

InChI=1S/C22H29N5O/c28-22(10-6-9-19-7-2-1-3-8-19)27-17-15-26(16-18-27)21-12-11-20(23-24-21)25-13-4-5-14-25/h1-3,7-8,11-12H,4-6,9-10,13-18H2

InChI Key

OQSDLIWMEGHKDQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07646649

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.757

Distribution Coefficient, logD

3.753

Water Solubility, LogSw

-4.02

Polar Surface Area

44.108

Acid Dissociation Constant (pKa)

22.47

Base Dissociation Constant (pKb)

7.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G856-8908 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G856-8908 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G856-8908?
Check Price and Availability of G856-8908, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G856-8908 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G856-8908
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G856-8908
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G856-8908 available by request