G857-0266 Screening compound: 3-[(4-bromobenzyl)sulfanyl]-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione

G857-0266 Screening compound: 3-[(4-bromobenzyl)sulfanyl]-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione
G857-0266 Screening compound: 3-[(4-bromobenzyl)sulfanyl]-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-0266
3-[(4-bromobenzyl)sulfanyl]-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-0266

Molecular Formula

C14H11BrN2O2S2 (C14 H11 BrN2 O2 S2)

Compound Name

3-[(4-bromobenzyl)sulfanyl]-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione

IUPAC name

3-{[(4-bromophenyl)methyl]sulfanyl}-4H-1lambda624-benzothiadiazine-11-dione

SMILES

O=S(c(cccc1)c1N1)(N=C1SCc(cc1)ccc1Br)=O

InChI

InChI=1S/C14H11BrN2O2S2/c15-11-7-5-10(6-8-11)9-20-14-16-12-3-1-2-4-13(12)21(18,19)17-14/h1-8H,9H2,(H,16,17)

InChI Key

SYBHSINOLWCWMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07651501

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.29

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.285

Distribution Coefficient, logD

3.251

Water Solubility, LogSw

-3.46

Polar Surface Area

52.706

Acid Dissociation Constant (pKa)

8.48

Base Dissociation Constant (pKb)

0.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

G857-0266 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G857-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-0266?
Check Price and Availability of G857-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-0266 available by request