G857-2056 Screening compound: 1-(4-{[1-(2-FLUOROPHENYL)-3,4-DIHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YL]SULFONYL}PHENYL)-1-ETHANONE

G857-2056 Screening compound: 1-(4-{[1-(2-FLUOROPHENYL)-3,4-DIHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YL]SULFONYL}PHENYL)-1-ETHANONE
G857-2056 Screening compound: 1-(4-{[1-(2-FLUOROPHENYL)-3,4-DIHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YL]SULFONYL}PHENYL)-1-ETHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-2056
1-(4-{[1-(2-FLUOROPHENYL)-3,4-DIHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YL]SULFONYL}PHENYL)-1-ETHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-2056

Molecular Formula

C21H19FN2O3S (C21 H19 FN2 O3 S)

Compound Name

1-(4-{[1-(2-FLUOROPHENYL)-3,4-DIHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YL]SULFONYL}PHENYL)-1-ETHANONE

IUPAC name

n/a

SMILES

CC(c(cc1)ccc1S(N(CCn1c2ccc1)C2c(cccc1)c1F)(=O)=O)=O

InChI

InChI=1S/C21H19FN2O3S/c1-15(25)16-8-10-17(11-9-16)28(26,27)24-14-13-23-12-4-7-20(23)21(24)18-5-2-3-6-19(18)22/h2-12,21H,13-14H2,1H3/t21-/m1/s1

InChI Key

MDHQKUYEURPSHE-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD07651590

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.689

Distribution Coefficient, logD

3.689

Water Solubility, LogSw

-3.92

Polar Surface Area

48.027

Acid Dissociation Constant (pKa)

21.69

Base Dissociation Constant (pKb)

-4.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

5.00

G857-2056 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with G857-2056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-2056?
Check Price and Availability of G857-2056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-2056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-2056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-2056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-2056 available by request