G863-0172 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide

G863-0172 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide
G863-0172 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0172
N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0172

Molecular Formula

C27H23N3O2S (C27 H23 N3 O2 S)

Compound Name

N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide

IUPAC name

N-{[6-(4-methylphenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}-9H-xanthene-9-carboxamide

SMILES

Cc(cc1)ccc1-c1c(CNC(C2c(cccc3)c3Oc3c2cccc3)=O)n(CCS2)c2n1

InChI

InChI=1S/C27H23N3O2S/c1-17-10-12-18(13-11-17)25-21(30-14-15-33-27(30)29-25)16-28-26(31)24-19-6-2-4-8-22(19)32-23-9-5-3-7-20(23)24/h2-13,24H,14-16H2,1H3,(H,28,31)

InChI Key

OODHKBZJNPHROV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09238953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.946

Distribution Coefficient, logD

4.946

Water Solubility, LogSw

-4.67

Polar Surface Area

42.445

Acid Dissociation Constant (pKa)

1.10

Base Dissociation Constant (pKb)

8.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G863-0172 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G863-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0172?
Check Price and Availability of G863-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0172 available by request