G863-0174 Screening compound: N-{[6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methyl}-1-cyclopropanecarboxamide

G863-0174 Screening compound: N-{[6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methyl}-1-cyclopropanecarboxamide
G863-0174 Screening compound: N-{[6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methyl}-1-cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0174
N-{[6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methyl}-1-cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0174

Molecular Formula

C17H19N3OS (C17 H19 N3 OS)

Compound Name

N-{[6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methyl}-1-cyclopropanecarboxamide

IUPAC name

N-{[6-(4-methylphenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}cyclopropanecarboxamide

SMILES

Cc(cc1)ccc1-c1c(CNC(C2CC2)=O)n(CCS2)c2n1

InChI

InChI=1S/C17H19N3OS/c1-11-2-4-12(5-3-11)15-14(10-18-16(21)13-6-7-13)20-8-9-22-17(20)19-15/h2-5,13H,6-10H2,1H3,(H,18,21)

InChI Key

HKMLSMJHYKPADM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09238955

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

313.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.013

Distribution Coefficient, logD

1.521

Water Solubility, LogSw

-3.20

Polar Surface Area

36.155

Acid Dissociation Constant (pKa)

12.61

Base Dissociation Constant (pKb)

8.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.18

G863-0174 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0174?
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What is the minimum amount of G863-0174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0174 available by request