G863-0280 Screening compound: 2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}acetamide

G863-0280 Screening compound: 2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}acetamide
G863-0280 Screening compound: 2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0280
2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0280

Molecular Formula

C19H22FN3OS (C19 H22 FN3 OS)

Compound Name

2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}acetamide

IUPAC name

2-cyclopentyl-N-{[6-(4-fluorophenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}acetamide

SMILES

O=C(CC1CCCC1)NCc1c(-c(cc2)ccc2F)nc2SCCn12

InChI

InChI=1S/C19H22FN3OS/c20-15-7-5-14(6-8-15)18-16(23-9-10-25-19(23)22-18)12-21-17(24)11-13-3-1-2-4-13/h5-8,13H,1-4,9-12H2,(H,21,24)

InChI Key

CBFTUMUSPMTAAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239019

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

359.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.703

Distribution Coefficient, logD

3.284

Water Solubility, LogSw

-4.06

Polar Surface Area

35.976

Acid Dissociation Constant (pKa)

12.21

Base Dissociation Constant (pKb)

7.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.40

G863-0280 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Anti-HIV1 Library (19540 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0280?
Check Price and Availability of G863-0280, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0280 available by request