G863-0316 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}cyclopropanecarboxamide

G863-0316 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}cyclopropanecarboxamide
G863-0316 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0316
N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0316

Molecular Formula

C16H16ClN3OS (C16 H16 ClN3 OS)

Compound Name

N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}cyclopropanecarboxamide

IUPAC name

N-{[6-(4-chlorophenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}cyclopropanecarboxamide

SMILES

O=C(C1CC1)NCc1c(-c(cc2)ccc2Cl)nc2SCCn12

InChI

InChI=1S/C16H16ClN3OS/c17-12-5-3-10(4-6-12)14-13(9-18-15(21)11-1-2-11)20-7-8-22-16(20)19-14/h3-6,11H,1-2,7-9H2,(H,18,21)

InChI Key

LNEGDRDVWUXKPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239033

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

333.84

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.184

Distribution Coefficient, logD

2.381

Water Solubility, LogSw

-3.77

Polar Surface Area

36.155

Acid Dissociation Constant (pKa)

12.61

Base Dissociation Constant (pKb)

8.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G863-0316 in Drug Discovery

Included in Screening Libraries

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0316 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0316?
Check Price and Availability of G863-0316, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0316 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0316
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0316
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0316 available by request