G868-1521 Screening compound: 2-(4-{[1,1'-BIPHENYL]-4-SULFONYL}PIPERAZIN-1-YL)-4-METHYL-6-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE

G868-1521 Screening compound: 2-(4-{[1,1'-BIPHENYL]-4-SULFONYL}PIPERAZIN-1-YL)-4-METHYL-6-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE
G868-1521 Screening compound: 2-(4-{[1,1'-BIPHENYL]-4-SULFONYL}PIPERAZIN-1-YL)-4-METHYL-6-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G868-1521
2-(4-{[1,1'-BIPHENYL]-4-SULFONYL}PIPERAZIN-1-YL)-4-METHYL-6-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G868-1521

Molecular Formula

C26H32N6O2S (C26 H32 N6 O2 S)

Compound Name

2-(4-{[1,1'-BIPHENYL]-4-SULFONYL}PIPERAZIN-1-YL)-4-METHYL-6-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE

IUPAC name

2-(4-{[11'-biphenyl]-4-sulfonyl}piperazin-1-yl)-4-methyl-6-(4-methylpiperazin-1-yl)pyrimidine

SMILES

Cc1nc(N(CC2)CCN2S(c(cc2)ccc2-c2ccccc2)(=O)=O)nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C26H32N6O2S/c1-21-20-25(30-14-12-29(2)13-15-30)28-26(27-21)31-16-18-32(19-17-31)35(33,34)24-10-8-23(9-11-24)22-6-4-3-5-7-22/h3-11,20H,12-19H2,1-2H3

InChI Key

SCFWONHPESFGBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165114

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.65

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.681

Distribution Coefficient, logD

4.111

Water Solubility, LogSw

-4.56

Polar Surface Area

58.635

Acid Dissociation Constant (pKa)

20.87

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G868-1521 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G868-1521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G868-1521?
Check Price and Availability of G868-1521, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G868-1521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G868-1521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G868-1521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G868-1521 available by request