G883-0157 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

G883-0157 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide
G883-0157 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0157
N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0157

Molecular Formula

C17H22N2O2 (C17 H22 N2 O2)

Compound Name

N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

IUPAC name

N-[(1-propanoyl-23-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

SMILES

CCC(N(CC1)c2c1cc(CNC(C1CCC1)=O)cc2)=O

InChI

InChI=1S/C17H22N2O2/c1-2-16(20)19-9-8-14-10-12(6-7-15(14)19)11-18-17(21)13-4-3-5-13/h6-7,10,13H,2-5,8-9,11H2,1H3,(H,18,21)

InChI Key

ALKPCEYHJOLGHJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643766

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

286.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.438

Distribution Coefficient, logD

1.438

Water Solubility, LogSw

-2.15

Polar Surface Area

40.598

Acid Dissociation Constant (pKa)

13.63

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.90

G883-0157 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Soluble Diversity Library (15920 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G883-0157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0157?
Check Price and Availability of G883-0157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0157 available by request