G883-0477 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-trimethoxybenzamide

G883-0477 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-trimethoxybenzamide
G883-0477 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-trimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0477
N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-trimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0477

Molecular Formula

C26H25ClN2O5 (C26 H25 ClN2 O5)

Compound Name

N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-trimethoxybenzamide

IUPAC name

N-{[1-(4-chlorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-345-trimethoxybenzamide

SMILES

COc1cc(C(NCc(cc2)cc(CC3)c2N3C(c(cc2)ccc2Cl)=O)=O)cc(OC)c1OC

InChI

InChI=1S/C26H25ClN2O5/c1-32-22-13-19(14-23(33-2)24(22)34-3)25(30)28-15-16-4-9-21-18(12-16)10-11-29(21)26(31)17-5-7-20(27)8-6-17/h4-9,12-14H,10-11,15H2,1-3H3,(H,28,30)

InChI Key

LLUVDTDYDBDPFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165393

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.054

Distribution Coefficient, logD

4.054

Water Solubility, LogSw

-4.57

Polar Surface Area

63.308

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G883-0477 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0477 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0477?
Check Price and Availability of G883-0477, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0477 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0477
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0477
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0477 available by request