G883-0495 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-triethoxybenzamide

G883-0495 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-triethoxybenzamide
G883-0495 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-triethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0495
N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-triethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0495

Molecular Formula

C29H31ClN2O5 (C29 H31 ClN2 O5)

Compound Name

N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3,4,5-triethoxybenzamide

IUPAC name

N-{[1-(4-chlorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-345-triethoxybenzamide

SMILES

CCOc1cc(C(NCc(cc2)cc(CC3)c2N3C(c(cc2)ccc2Cl)=O)=O)cc(OCC)c1OCC

InChI

InChI=1S/C29H31ClN2O5/c1-4-35-25-16-22(17-26(36-5-2)27(25)37-6-3)28(33)31-18-19-7-12-24-21(15-19)13-14-32(24)29(34)20-8-10-23(30)11-9-20/h7-12,15-17H,4-6,13-14,18H2,1-3H3,(H,31,33)

InChI Key

DTKFLJASKXZYDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165407

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

523.03

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.013

Distribution Coefficient, logD

5.013

Water Solubility, LogSw

-5.13

Polar Surface Area

62.048

Acid Dissociation Constant (pKa)

14.09

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.00

G883-0495 in Drug Discovery

Included in Screening Libraries

Human Proteases Annotated Library (2868 compounds)

Human Receptors Annotated Library (5376 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0495?
Check Price and Availability of G883-0495, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0495 available by request