G883-0510 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetamide

G883-0510 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetamide
G883-0510 Screening compound: N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0510
N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0510

Molecular Formula

C26H22ClN3O4 (C26 H22 ClN3 O4)

Compound Name

N-{[1-(4-chlorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetamide

IUPAC name

N-{[1-(4-chlorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-2-(3-oxo-34-dihydro-2H-14-benzoxazin-4-yl)acetamide

SMILES

O=C(CN1c(cccc2)c2OCC1=O)NCc(cc1)cc(CC2)c1N2C(c(cc1)ccc1Cl)=O

InChI

InChI=1S/C26H22ClN3O4/c27-20-8-6-18(7-9-20)26(33)29-12-11-19-13-17(5-10-21(19)29)14-28-24(31)15-30-22-3-1-2-4-23(22)34-16-25(30)32/h1-10,13H,11-12,14-16H2,(H,28,31)

InChI Key

LYZVAOBLBKMRBB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165411

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.93

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.292

Distribution Coefficient, logD

3.292

Water Solubility, LogSw

-3.79

Polar Surface Area

64.219

Acid Dissociation Constant (pKa)

13.87

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

G883-0510 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0510 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0510?
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What is the minimum amount of G883-0510 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0510
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0510
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0510 available by request