G883-0601 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

G883-0601 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide
G883-0601 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0601
N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0601

Molecular Formula

C21H22N2O2 (C21 H22 N2 O2)

Compound Name

N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

IUPAC name

N-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]cyclobutanecarboxamide

SMILES

O=C(C1CCC1)NCc(cc1)cc(CC2)c1N2C(c1ccccc1)=O

InChI

InChI=1S/C21H22N2O2/c24-20(16-7-4-8-16)22-14-15-9-10-19-18(13-15)11-12-23(19)21(25)17-5-2-1-3-6-17/h1-3,5-6,9-10,13,16H,4,7-8,11-12,14H2,(H,22,24)

InChI Key

HOUPPMIADPGOLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165428

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.229

Distribution Coefficient, logD

2.229

Water Solubility, LogSw

-2.72

Polar Surface Area

40.854

Acid Dissociation Constant (pKa)

13.63

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G883-0601 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G883-0601 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0601?
Check Price and Availability of G883-0601, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0601 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0601
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0601
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0601 available by request