G883-0606 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-3,5-dimethoxybenzamide

G883-0606 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-3,5-dimethoxybenzamide
G883-0606 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-3,5-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0606
N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-3,5-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0606

Molecular Formula

C25H24N2O4 (C25 H24 N2 O4)

Compound Name

N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-3,5-dimethoxybenzamide

IUPAC name

N-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-35-dimethoxybenzamide

SMILES

COc1cc(C(NCc(cc2)cc(CC3)c2N3C(c2ccccc2)=O)=O)cc(OC)c1

InChI

InChI=1S/C25H24N2O4/c1-30-21-13-20(14-22(15-21)31-2)24(28)26-16-17-8-9-23-19(12-17)10-11-27(23)25(29)18-6-4-3-5-7-18/h3-9,12-15H,10-11,16H2,1-2H3,(H,26,28)

InChI Key

OFMHNIMWHCQESG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165432

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.839

Distribution Coefficient, logD

3.839

Water Solubility, LogSw

-4.02

Polar Surface Area

55.418

Acid Dissociation Constant (pKa)

13.78

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G883-0606 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0606 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0606?
Check Price and Availability of G883-0606, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0606 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0606
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0606
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0606 available by request